One-word Substitution

Easy Level

  1. A person who works with you: Colleague
  2. A person who is not easily convinced: Skeptic
  3. A person who helps another: Benefactor
  4. A person who lives in a foreign country: Expatriate
  5. A person who studies the stars and planets: Astronomer
  6. A person who loves books: Bibliophile
  7. A person who leads a group: Leader
  8. A person who prepares and sells medicines: Pharmacist
  9. A person who paints or draws: Artist
  10. A person who writes books: Author
  11. A person who repairs vehicles: Mechanic
  12. A person who mends shoes: Cobbler
  13. A person who fights fires: Firefighter
  14. A person who teaches in school: Teacher
  15. A person who treats sick people: Doctor
  16. A person who flies an aircraft: Pilot
  17. A person who acts in movies: Actor
  18. A person who directs a movie: Director
  19. A person who runs a business: Entrepreneur
  20. A person who steals things: Thief
  21. A person who makes bread: Baker
  22. A person who grows crops: Farmer
  23. A person who catches fish: Fisherman
  24. A person who sells goods: Vendor
  25. A person who plays a musical instrument: Musician
  26. A person who writes poems: Poet
  27. A person who builds houses: Builder
  28. A person who designs buildings: Architect
  29. A person who installs and repairs electrical systems: Electrician
  30. A person who serves food in a restaurant: Waiter
  31. A person who makes clothing: Tailor
  32. A person who takes care of teeth: Dentist
  33. A person who plays sports: Athlete
  34. A person who sells meat: Butcher
  35. A person who attends to passengers on an aircraft: Flight attendant
  36. A person who takes photographs: Photographer
  37. A person who trades in goods: Merchant
  38. A person who cuts hair: Barber
  39. A person who repairs machines: Mechanic
  40. A person who operates a train: Conductor
  41. A person who writes news: Journalist
  42. A person who composes music: Composer
  43. A person who studies human societies: Anthropologist
  44. A person who investigates crimes: Detective
  45. A person who digs for minerals: Miner
  46. A person who controls an organization: Manager
  47. A person who takes legal action: Litigant
  48. A person who receives something: Recipient
  49. A person who watches a show: Spectator
  50. A person who finds new things: Explorer
  51. A person who changes sides: Defector
  52. A person who leads a country: President
  53. A person who studies animals: Zoologist
  54. A person who works in a laboratory: Technician
  55. A person who speaks for others: Spokesperson
  56. A person who saves money: Saver
  57. A person who predicts the future: Soothsayer
  58. A person who runs in elections: Candidate
  59. A person who has total control: Dictator
  60. A person who operates heavy machinery: Operator
  61. A person who guides tourists: Guide
  62. A person who funds a project: Sponsor
  63. A person who heals wounds: Healer
  64. A person who knows many languages: Polyglot
  65. A person who performs magic: Magician
  66. A person who studies rocks: Geologist
  67. A person who writes music: Lyricist
  68. A person who is good at painting: Painter
  69. A person who plays a role in a play: Actor
  70. A person who studies insects: Entomologist
  71. A person who makes sculptures: Sculptor
  72. A person who treats animals: Veterinarian
  73. A person who makes maps: Cartographer
  74. A person who fixes computers: IT specialist
  75. A person who works in the armed forces: Soldier
  76. A person who sculpts stone: Mason
  77. A person who works with wood: Carpenter
  78. A person who sails a ship: Sailor
  79. A person who serves in an army: Soldier
  80. A person who guards buildings: Security guard
  81. A person who practices law: Lawyer
  82. A person who performs in a circus: Acrobat
  83. A person who arranges flowers: Florist
  84. A person who sells newspapers: Newsagent
  85. A person who mends clothes: Seamstress
  86. A person who presides over court: Judge
  87. A person who repairs pipes: Plumber
  88. A person who delivers mail: Postman
  89. A person who designs clothes: Fashion designer
  90. A person who studies the environment: Ecologist
  91. A person who manages money: Accountant
  92. A person who makes pottery: Potter
  93. A person who sells fruits and vegetables: Greengrocer
  94. A person who presents news: Anchor
  95. A person who translates spoken words: Interpreter
  96. A person who maintains law and order: Police officer
  97. A person who plays the violin: Violinist
  98. A person who creates websites: Web developer
  99. A person who delivers babies: Midwife
  100. A person who specializes in skin diseases: Dermatologist

Medical

  1. Abrasion – Scrape of the skin
  2. Abscess – Pus-filled swelling
  3. Acidosis – Excess acid in the body
  4. Acrophobia – Fear of heights
  5. Adipose – Fatty tissue
  6. Aerophagia – Swallowing air
  7. Agnosia – Loss of sensory recognition
  8. Agraphia – Inability to write
  9. Ailurophobia – Fear of cats
  10. Alopecia – Hair loss
  11. Amenorrhea – Absence of menstruation
  12. Analgesic – Pain-relieving drug
  13. Anemia – Deficiency of red blood cells
  14. Anesthesia – Loss of sensation
  15. Aneurysm – Bulging of an artery
  16. Angina – Chest pain
  17. Anorexia – Loss of appetite
  18. Antacid – Drug that reduces stomach acid
  19. Antibiotic – Infection-fighting drug
  20. Anticoagulant – Blood-thinning agent
  21. Antipyretic – Fever-reducing drug
  22. Aphasia – Loss of speech ability
  23. Apnea – Temporary stoppage of breathing
  24. Arteriosclerosis – Hardening of arteries
  25. Arthritis – Joint inflammation
  26. Aspiration – Inhalation of foreign matter
  27. Asphyxia – Suffocation
  28. Astigmatism – Blurred vision defect
  29. Astringent – Skin-tightening agent
  30. Ataxia – Loss of muscle coordination
  31. Atony – Lack of muscle tone
  32. Atrophy – Wasting away of tissues
  33. Autopsy – Examination of a dead body
  34. Bactericidal – Bacteria-killing agent
  35. Benign – Non-cancerous tumor
  36. Biopsy – Tissue sample examination
  37. Bradycardia – Slow heart rate
  38. Bronchitis – Inflammation of bronchi
  39. Cachexia – Severe weight loss
  40. Calculus – Stone in the body
  41. Carcinoma – Malignant tumor
  42. Cardiomegaly – Enlarged heart
  43. Catalepsy – Rigid unconscious state
  44. Catheter – Tube for fluid drainage
  45. Cauterization – Burning tissue to stop bleeding
  46. Cellulitis – Skin infection
  47. Cerebritis – Brain inflammation
  48. Cholelithiasis – Gallstones
  49. Colitis – Inflammation of the colon
  50. Coma – Deep unconscious state
  51. Conjunctivitis – Inflammation of the eye membrane
  52. Constipation – Difficulty in passing stools
  53. Contusion – Bruise
  54. Cyanosis – Bluish skin discoloration
  55. Cystitis – Bladder inflammation
  56. Debridement – Removal of dead tissue
  57. Dehydration – Loss of body fluids
  58. Delirium – Confusion and hallucination
  59. Dementia – Memory loss disorder
  60. Dermatitis – Skin inflammation
  61. Diabetes – High blood sugar condition
  62. Diarrhea – Frequent loose stools
  63. Diplopia – Double vision
  64. Dyslexia – Reading disorder
  65. Dyspnea – Difficulty breathing
  66. Dystrophy – Muscle degeneration
  67. Edema – Swelling due to fluid retention
  68. Embolism – Blocked blood vessel
  69. Emesis – Vomiting
  70. Encephalitis – Brain inflammation
  71. Endoscope – Instrument for internal examination
  72. Epistaxis – Nosebleed
  73. Epilepsy – Seizure disorder
  74. Erythema – Skin redness
  75. Febrile – Feverish condition
  76. Fibrosis – Thickening of tissues
  77. Fistula – Abnormal passage in the body
  78. Fracture – Broken bone
  79. Gangrene – Tissue death
  80. Gastritis – Stomach inflammation
  81. Glaucoma – Eye disease causing blindness
  82. Glycosuria – Sugar in urine
  83. Goiter – Enlarged thyroid gland
  84. Hemangioma – Blood vessel tumor
  85. Hematemesis – Vomiting blood
  86. Hematuria – Blood in urine
  87. Hemophilia – Blood clotting disorder
  88. Hepatitis – Liver inflammation
  89. Hernia – Organ protrusion
  90. Hypertension – High blood pressure
  91. Hypotension – Low blood pressure
  92. Hypoxia – Lack of oxygen
  93. Immunity – Resistance to disease
  94. Jaundice – Yellowing of skin
  95. Laceration – Deep cut or wound
  96. Leukemia – Blood cancer
  97. Meningitis – Brain membrane inflammation
  98. Metastasis – Cancer spread
  99. Neuropathy – Nerve damage
  100. Xerosis – Dry skin condition.

Higher Level

  1. Agnostic – One who is unsure about God’s existence
  2. Altruist – One who is selflessly concerned for others
  3. Ambidextrous – One who can use both hands equally well
  4. Amiable – One who is friendly and pleasant
  5. Anarchist – One who opposes government and laws
  6. Ascetic – One who practices self-denial and simplicity
  7. Autocrat – One who rules with absolute power
  8. Bigot – One who is intolerant of others’ beliefs
  9. Bibliophile – One who loves books
  10. Bohemian – One who lives an unconventional lifestyle
  11. Bureaucrat – One who follows rigid administrative procedures
  12. Cannibal – One who eats human flesh
  13. Cartographer – One who draws maps
  14. Censor – One who removes offensive content
  15. Chauvinist – One who is blindly patriotic
  16. Connoisseur – One who has expert knowledge in a field
  17. Conscript – One who is forcibly enrolled in the army
  18. Contortionist – One who can twist their body flexibly
  19. Cosmopolitan – One who is at home anywhere in the world
  20. Credulous – One who is easily deceived
  21. Crusader – One who campaigns for a cause
  22. Cynic – One who doubts human sincerity
  23. Demagogue – One who stirs people’s emotions for power
  24. Dipsomaniac – One who has an uncontrollable craving for alcohol
  25. Egoist – One who thinks only of themselves
  26. Egotist – One who always talks about themselves
  27. Elderly – One who is old or aged
  28. Emigrant – One who leaves their country to settle elsewhere
  29. Enthusiast – One who is highly interested in something
  30. Epicure – One who enjoys fine food and drink
  31. Epitaph – Words inscribed on a tombstone
  32. Fatalist – One who believes in destiny
  33. Fanatic – One who has extreme beliefs
  34. Fastidious – One who is very particular and fussy
  35. Feminist – One who advocates for women’s rights
  36. Flamboyant – One who is showy and extravagant
  37. Foreman – One who supervises workers
  38. Fugitive – One who runs away from the law
  39. Gastronomist – One who is an expert in food and cooking
  40. Glutton – One who eats excessively
  41. Gourmet – One who appreciates fine food
  42. Hedonist – One who lives for pleasure
  43. Heretic – One who opposes religious norms
  44. Hermit – One who lives in solitude
  45. Honorary – One who receives a position without responsibilities
  46. Horologist – One who studies or repairs clocks and watches
  47. Hostage – One who is held captive for ransom
  48. Humanitarian – One who promotes human welfare
  49. Hypocrite – One who pretends to have virtues they lack
  50. Iconoclast – One who challenges traditional beliefs
  51. Idolater – One who worships idols
  52. Illiterate – One who cannot read or write
  53. Immigrant – One who moves into a new country
  54. Impostor – One who pretends to be someone else
  55. Incorrigible – One who cannot be corrected
  56. Infidel – One who does not believe in a particular religion
  57. Insomniac – One who has difficulty sleeping
  58. Intellectual – One who is highly knowledgeable
  59. Introvert – One who prefers solitude
  60. Itinerant – One who travels from place to place
  61. Jingoist – One who is extremely patriotic and warlike
  62. Kleptomaniac – One who has an uncontrollable urge to steal
  63. Laggard – One who is slow and lazy
  64. Libertarian – One who advocates personal freedom
  65. Linguist – One who knows multiple languages
  66. Lunatic – One who is insane
  67. Magnate – One who is powerful and influential in business
  68. Martyr – One who sacrifices their life for a cause
  69. Masochist – One who enjoys pain
  70. Materialist – One who values material possessions
  71. Maverick – One who is independent and unconventional
  72. Megalomaniac – One who has a delusion of grandeur
  73. Melancholic – One who is constantly sad
  74. Mercenary – One who fights for money
  75. Misanthrope – One who dislikes people
  76. Misogynist – One who hates women
  77. Monogamist – One who believes in one marriage at a time
  78. Monotheist – One who believes in only one God
  79. Mortician – One who prepares dead bodies for burial
  80. Multilingual – One who speaks many languages
  81. Narcissist – One who excessively admires themselves
  82. Nationalist – One who strongly supports their country
  83. Naturalist – One who studies nature
  84. Neophyte – One who is new to a subject
  85. Nomad – One who moves from place to place
  86. Novice – One who is inexperienced
  87. Omnivore – One who eats both plants and meat
  88. Optimist – One who sees the positive side of things
  89. Orator – One who is skilled in public speaking
  90. Pacifist – One who believes in non-violence
  91. Pagan – One who follows a polytheistic religion
  92. Paragon – One who is a perfect example of something
  93. Paranoid – One who is overly suspicious
  94. Pauper – One who is extremely poor
  95. Pedestrian – One who walks on foot
  96. Pessimist – One who expects the worst
  97. Philanderer – One who flirts recklessly
  98. Philanthropist – One who donates for the welfare of others
  99. Polygamist – One who has multiple spouses
  100. Veteran – One who has long experience in a field

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