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Remarkably, 2 months after antidepressant discontinuation, Ms Adrian started experiencing menstrual irregularity and hair growth. Ten months later, MDD recurred. During the next 4 years, she was on treatment with escitalopram at 20 mg/d and remained symptom-free. Meanwhile, she achieved notable menstrual cycle improvement and reduction in hirsutism. As Ms Adrian was feeling well, she stopped taking the medication on her own and her menstrual complaints immediately recurred. She restarted escitalopram in 4 months, and her PCOS symptoms remitted again. This was the longest regular menstrual cycle period she had ever had with no use of oral contraceptive pills. Last year, her ultrasounds continued to show polycystic ovaries.
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What does Ms Adrian’s case suggest?
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People like her can never achieve remission without medication.
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Remission is possible with medication but they are short-lived.
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Patients should stop relying on medication like escitalopram for a longer relief.
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It is better for patients with PCOS not to stop medication.
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