Day 9 – Medical Terms & Abbreviations

Systemic sclerosis (SSc) is a disorder of the connective tissue characterized by fibrosis of the skin, vascular abnormalities, and presence of autoantibodies. It is characterized by excessive deposition of extracellular matrix. Therefore, there is significant heterogeneity in organ progression and prognosis. Interstitial lung disease (ILD) is a heterogeneous group of parenchymal lung disorders that share common radiologic, pathologic, and clinical manifestations. It is characterized by lung parenchyma damage, accompanied by inflammation and fibrosis, and fibrosis is often incurable. The fibrosing forms of ILD are often incurable, and are associated with significant morbidity and mortality. SSc is often accompanied by ILD. The incidence of SSc-ILD in the relevant literature ranges from 45% to 90%. A recent European League Against Rheumatism Scleroderma Trials and Research analysis revealed in a cohort of 3,656 SSc patients that ILD was present in 53% of cases with diffuse cutaneous SSc and in 35% of cases with limited cutaneous SSc.

  1. Connective tissue
    1. Tissue that supports, protects, and gives structure to other tissues and organs in the body
  2. Characterized by
    1. Having the qualities of something
  3. Autoantibodies
    1. Antibodies (immune proteins) that mistakenly target and react with a person’s own tissues or organs
  4. Excessive
    1. More than is necessary
  5. Deposition
    1. Removal
  6. Extracellular matrix
    1. The non-cellular component present within all tissues and organs
  7. Therefore
    1. For that reason
  8. Significant
    1. Important
  9. Heterogeneity
    1. the quality or state of being diverse in character or content.
  10. Progression
    1. the process of developing or moving gradually towards a more advanced state
  11. Prognosis
    1. the likely course of a medical condition.
    2. Improvement in a medical condition
    3. Relapse of a medical condition
  12. Pathology
    1. the study of the causes and effects of disease or injury
  13. Clinical manifestations
    1. Symptoms of an ailment
    2. Solutions for a disease
    3. Curing a disease
  14. Inflammation
    1. Part of the body becoming reddened, swollen, hot, and often painful, especially as a reaction to injury or infection
  15. Morbidity
  16. Mortality
  17. Incidence
  18. Relevant literature
  19. Cohort
  20. Diffuse cutaneous SSc
  21. Interstitial lung disease (ILD)
  22. Parenchymal lung disorders
  23. Fibrosis of the skin
  24. Systemic sclerosis (SSc)
  25. Vascular abnormalities

Written by Biju John

Love for English begins with understanding its unknown rules. Biju John lives on the internet, teaching OET, IELTS and PTE. More than a million students have thanked him from their heart.

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